SARS-COV-2 ACHIEVES IMMUNE ESCAPE BY DESTROYING MITOCHONDRIAL QUALITY: COMPREHENSIVE ANALYSIS OF THE CELLULAR LANDSCAPES OF LUNG AND BLOOD SPECIMENS FROM PATIENTS WITH COVID-19

Mitochondria get caught in the crossfire of coronavirus disease 2019 (COVID-19) and antiviral immunity.The mitochondria-mediated antiviral immunity represents the host’s first line of defense against viral infection, and the mitochondria are important targets of COVID-19.However, the specific manifestations of mitochondrial damage in patients wit

This paper is dedicated to achieving flexible automatic assembly of miniature circuit breakers (MCBs) to resolve the high rigidity issue of existing MCB assembly by proposing a flexible automatic assembly process and method with industrial robots.To optimize the working performance of the robot, a time-optimal trajectory planning method of the impr

ABSTRACT Conjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria.To deliver the DNA substrate to recipient cells, it must cross the cell envelopes of both donor and recipient bacteria.In the T4SS from the enterococcal conjugative plasmid pCF10, PrgK is known to